: Aldema Sas-Chen, Justin M. Thomas, Donna Matzov, Masato Taoka, Kellie D. Nance, Ronit Nir, Keri M. B...
Quantitative nucleotide resolution profiling of RNA
2021326 · In addition, it may be possible to integrate ac4C-seq with other hydride-based sequencing methods to simultaneously profile additional modified nucleobases
This approach enables the sensitive, PCR-amplifiable detection of individual ac4C sites from nanograms of unfractionated cellular RNA. The sensitive and quantitative nature of this
2020617 · Ac4C is markedly induced in response to increases in temperature, and acetyltransferase-deficient archaeal strains exhibit temperature-dependent growth defects. ... we used ac 4 C-seq to profile ...
XG-ac4C: identification of N4-acetylcytidine (ac4C) in
2020121 · N4-acetylcytidine (ac4C) is a post-transcriptional modification in mRNA which plays a major role in the stability and regulation of mRNA translation. The working mechanism of ac4C modification in ...
Emerging role of N4-acetylcytidine modification of RNA in
20201110 · Although the ac4C ‘writer’ has been well studied and functionally characterized, the identities of ac4C ‘erasers’, ac4C ‘readers’ and molecular regulators of ac4C deposition on RNAs are still elusive and needs further investigation. ... Additionally, the urinary metabolome profile of pregnant women of GDM showed that metabolism of ...
This approach enables the sensitive, PCR-amplifiable detection of individual ac4C sites from nanograms of unfractionated cellular RNA. The sensitive and quantitative nature of this assay provides a powerful tool to understand how cytidine acetylation is targeted, profile RNA acetyltransferase dynamics, and validate the sites and stoichiometry of ac4C in
2020617 · N4-acetylcytidine (ac4C) is an ancient and highly conserved RNA modification that is present on tRNA and rRNA and has recently been investigated in eukaryotic mRNA1–3. However, the
XG-ac4C: identification of N4-acetylcytidine (ac4C) in
2020121 · N4-acetylcytidine (ac4C) is a post-transcriptional modification in mRNA which plays a major role in the stability and regulation of mRNA translation. The working mechanism of ac4C modification in ...
PACES: prediction of N4-acetylcytidine (ac4C) modification
2019731 · N4-acetylcytidine (ac4C) is a highly conserved RNA modification and is the first acetylation event described in mRNA. ac4C in mRNA has been demonstrated to be involved in the regulation of mRNA ...
Emerging role of N4-acetylcytidine modification of RNA in
20201110 · Although the ac4C ‘writer’ has been well studied and functionally characterized, the identities of ac4C ‘erasers’, ac4C ‘readers’ and molecular regulators of ac4C deposition on RNAs are still elusive and needs further investigation. ... Additionally, the urinary metabolome profile of pregnant women of GDM showed that metabolism of ...
2020617 · N4-acetylcytidine (ac4C) is an ancient and highly conserved RNA modification that is present on tRNA and rRNA and has recently been investigated in eukaryotic mRNA1–3. However, the
Quantitative nucleotide resolution profiling of RNA
2021326 · In addition, it may be possible to integrate ac4C-seq with other hydride-based sequencing methods to simultaneously profile additional modified nucleobases including m7G 25,26, further expanding ...
PACES: prediction of N4-acetylcytidine (ac4C) modification
2019731 · N4-acetylcytidine (ac4C) is a highly conserved RNA modification and is the first acetylation event described in mRNA. ac4C in mRNA has been demonstrated to be involved in the regulation of mRNA ...
Emerging role of N4-acetylcytidine modification of RNA in
20201110 · Although the ac4C ‘writer’ has been well studied and functionally characterized, the identities of ac4C ‘erasers’, ac4C ‘readers’ and molecular regulators of ac4C deposition on RNAs are still elusive and needs further investigation. ... Additionally, the urinary metabolome profile of pregnant women of GDM showed that metabolism of ...
This approach enables the sensitive, PCR-amplifiable detection of individual ac4C sites from nanograms of unfractionated cellular RNA. The sensitive and quantitative nature of this assay provides a powerful tool to understand how cytidine acetylation is targeted, profile RNA acetyltransferase dynamics, and validate the sites and stoichiometry of ac4C in